Wednesday, November 23, 2011

Making the World a better place for our kids by Donating cpu cycles!



The Help Fight Childhood Cancer comes to you from the Chiba Cancer Center Research Institute, which is affiliated to Chiba University, located in Chiba prefecture, Japan.

As the name of the project implies, the focus of this project is to try to find novel drugs to treat childhood cancers, namely neuroblastoma.

Neuroblastoma is one of the most frequently occurring solid tumors in children, especially in the first two years of their life, and its clinical outcome is still very poor. 

With your help, we hope to do the initial research which could result in discoveries that could lead to the development of novel drugs to treat these complex pediatric tumors.

Although, we expect to finish the project in about 2 years on World Community Grid, your contribution is appreciated as it would take us over 100 years on the computers available to us to finish this computation. Join now!

Latest News from The Help Fight Childhood Cancer project:


After screening 3,000,000 candidate chemicals by molecular imaging and cellular toxicity, our project team has finally identified 7 small chemical compounds which kill several neuroblastoma cells at very low concentration.

From: HFCC

Friday, November 18, 2011

Cancer Wellness Programs: Recovery Through Fitness

Cancer Wellness Programs: Recovery Through Fitness 


   Exercise plays an important role in health and wellness programs, especially for those who have lost their health to cancer. Many cancer recovery programs focus on reclaiming health and wellness through exercise and meditation. They are always tailored to meet the needs of individual cancer patients. Just about anyone can benefit, from breast cancer survivors to those facing rare and trying mesothelioma treatment.

   Cancer wellness programs provide many of the same benefits other exercise programs offer -- better circulation, stronger muscles, and improved energy and stamina. But their benefits go beyond the physical. Cancer patients who engage in exercise experience a decreased isolation, for example, and a remarkable sense of empowerment.

Physical Benefits

   Many cancer patients view their fitness recovery programs as motivating and inspiring. They credit cancer wellness programs with helping them “get back into life,” at a time when it may be hard to get out of bed.

   Conventional treatments are proven to fight cancer aggressively. But patients are usually left with negative side effects, including pain, nausea; sleep problems, anxiety, and depression. Exercise helps patients tolerate treatment better, and it helps them sleep better. In fact, moderate exercise during the treatment phase can alleviate physical pain and eliminate the need for anti-depressants or anti-anxiety medications.

Empowerment

    For most people, undergoing cancer treatment means losing control and power over their own body. Fitness programs, whether they involve gentle stretching movements or more involved exercise, serve to empower cancer survivors.

Motivation

    Motivation is a huge benefit of cancer wellness programs. When cancer patients are motivated to participate in exercise and meditation, they are typically motivated to continue their cancer treatment. They are more inspired and motivated in life, in general, which helps in the recovery process.

Balance

   Many people who managed to maintain physical fitness before cancer are surprised to learn they have lost their sense of balance during treatment. Wellness programs help them find that balance. Classes generally involve balance work and core strength, as well as cardio work and other strengthening exercises. Meditation and affirmation help patients stay focuses and grounded.

According to the National Cancer Institute, physical activity can reduce the risk for developing cancer. Colorectal cancer is one of the more extensively studied cancers with regard to exercise. But fitness is important for people with all cancer types, including endometrial, prostate, mesothelioma, and lung cancers.

Cancer patients are encouraged to stay active between fitness classes, and to continue their exercise work at home. Not only do cancer wellness programs strengthen patients physically, but they also provide emotional and spiritual strength. They also give patients a sense of belonging, so they know they are not alone.


By:
Guest Blogger
David Haas
http://www.mesothelioma.com/blog

Tuesday, November 15, 2011

Happy 7th Birthday, World Community Grid!



World Community Grid is 7 years of age today, November 16, 2011, and kudos go to all of our members for donating their computer power each and every day to advance critical humanitarian research!

Since last year, we have accomplished the following:

Looking at the numbers: The following statistical growth was accomplished. (To see the current statistics click here).

  • Members: 44,000 new members registered

  • Devices: 241,000 new devices were registered

  • Computer Run Time: 120,000 years of computer run time were donated

  • Points: 121 Billion points were awarded

  • Research Results: 243 Million results were returned

    Active Research Projects:
    During the last 12 months, World Community Grid continued running the following research projects. Click on the project name to find out more about each project:

  • Drug Search for Leishmaniasis

  • Computing for Clean Water

  • The Clean Energy Project - Phase 2

  • Discovering Dengue Drugs - Together - Phase 2

  • Help Cure Muscular Dystrophy - Phase 2

  • Help Fight Childhood Cancer

  • Help Conquer Cancer

  • Human Proteome Folding - Phase 2

  • FightAIDS@Home

    New Research Projects:
    During the last 12 months, World Community Grid launched the following research projects. Click on the project name to find out more about each project:

  • GO Fight Against Malaria

  • Drug Search for Leishmaniasis

    Future project queue:
    Proposals for nine additional research projects have been received and are being reviewed at this time. Two of these research projects were announced in a September 7, 2010 press release. The remainder of the projects in review will be announced at launch time.

    Additional accomplishments:
    The following is a list of additional accomplishments:

  • World Community Grid recognized as one of IBM's 100 Icons of Progress

  • World Community Grid research scientists awarded portion of IBM Watson Jeopardy! winnings

  • Expanded ability to handle growth by taking advantage of the IBM SmartCloud Enterprise

  • 30 Peer Reviewed Research Papers

  • 27 World Community Grid Videos

  • 4 Lecture Series Webcasts: Read more...
  • Monday, November 14, 2011

    New World Community Grid project: Go fight against Malaria.



    Mission
    The mission of the GO Fight Against Malaria project is to discover promising drug candidates that could be developed into new drugs that cure drug resistant forms of malaria. The computing power of World Community Grid will be used to perform computer simulations of the interactions between millions of chemical compounds and certain target proteins, to predict their ability to eliminate malaria. The best compounds will be tested and further developed into possible treatments for the disease.

    Significance
    Malaria is one of the three deadliest infectious diseases on earth and is caused by parasites that infect both humans and animals. Female mosquitoes spread the disease by biting infected hosts and passing the parasites to other hosts that they bite later. When these parasites replicate themselves in red blood cells (which the parasites use for food), the symptoms of malaria appear. Malaria initially causes fevers and headaches, and in severe cases it leads to comas or death. Plasmodium falciparum, the parasite that causes the deadliest form of malaria, kills more people than any other parasite on the planet. Over 3 billion people are at risk of being infected with malaria.

    Although there are many approved drugs that are able to cure malarial infections, multi-drug-resistant mutant "superbugs" exist that are not eliminated by the current drugs. Because new mutant superbugs keep evolving and spreading throughout the world, discovering and developing new types of drugs that can cure infections by these multi-drug-resistant mutant strains of malaria is a significant global health priority.


    Approach
    Scientists at The Scripps Research Institute of La Jolla, California, U.S.A., will use IBM's World Community Grid to computationally evaluate millions of candidate compounds against different molecular drug targets from the malaria parasite. If these target molecules can be disabled, then patients infected with malaria can potentially be cured. The computations will estimate the ability of the candidate compounds to disable the particular target molecules needed by the malaria parasite to survive and multiply. Particular priority will be given to targets and candidate compounds which could attack the multi-drug-resistant mutant "superbug" strains of the malaria parasite. The power of World Community Grid can reduce to one (1) year what would take at least one hundred (100) years to complete using the resources normally available to the researchers at The Scripps Research Institute. The results computed on World Community Grid will be available in the public domain for all scientists to use and build upon in their research to develop drugs to fight malaria.

    Two weeks with FX-8120 Bulldozer and Corsair H100

       Almost two weeks with FX-8120 Bulldozer and Corsair H100 now.
    I have been running Boinc 24/7 with 100% usage for FX-8120,AMD Powercolor 6870 and Nvidia Palit GTX 460 1gb. World Community Grid with Cpu, Moo!wrapper with AMD Powercolor 6870 and Primegrid with Nvidia Palit GTX 460 1gb. Just smooth crunching and I can use internet,Youtube and do all the things i usually do, even PC is crunching Boinc tasks with 100% system usage.


        Corsair H100 does good job keeping FX-8120 temps down. I replaced Corsair H100 original fans with two Scythe Gentle Typhoon 1850 rpm fans, because of the noise original fans made and did see temps drop 2 C with Scythe Gentle Typhoons as well.
    While crunching no cpu related temperature have past 53 C/127 F. Note: FX-8120 is overclocked to 4 Ghz with two overclocked Gpus with 100% usage in not so big Xigmatek Midgard Midi case. System is powered by very solid and silent PSU Thermaltake ToughPower XT 775W . Motherboard is Gigabyte GA-970A-UD3 and Gigabyte motherboards are perfect with good VRM.

    Here is a good review from Corsair H100

    Thursday, November 10, 2011

    My efforts against Childhood Cancer Team is advancing in Boinc Finnish Team standings!


    My efforts against Childhood Cancer Team is in 7th place in Boinc Finnish team standings and we are gaining 6th place team fast.

    Check out our team stats HERE!

    Thank you to our members and happy crunching for a good cause.

    LTDAkiles
    Email: Akiles@windowslive.com

    Wednesday, November 9, 2011

    One way to make world better place for our kids.


    Easiest way to help scientist reaserch important projects like Help fight childhood cancer or conquer cancer is to join Boinc Grid Computing.
    Grid Computing  is basically an oversized networked computer that allows a problem to be split into thousands of little problems and hundreds of computer’s (home pc’s, laptops, anything except mobile devices). By distributing an enormous problem to many systems, it can be solved faster and more accurately than relying on a single system to tackle the computations involved.


    Use the idle time on your computer (Windows, Mac, or Linux) to cure diseases, study global warming, discover pulsars, and do many other types of scientific research. It's safe, secure, and easy:
    1. Download and run BOINC software
    2. Enter an email address and password. 
    3. Once Boinc software is running choose advanced view.
    4.  Go to Tools and choose add project.
    5.  Choose Project interesting you and add your email and create a password as new user.
    6.  Now Boinc starts to download a workunit for your pc to calculate and you are directed to projects your profile page asking your country and Team. To the team spot add "My efforts against childhood cancer". If some projects don't have a team option here, you can see "Find a team" spot page which comes after you have saved your alias.
    7. Now you are in your profile page of project of your choosing. You can setup how your's is beeing used,when,how much and how many cores/gpus. You can leave those alone if it's all new to you.
    8.  You're done. Just let your computer do it's job and remember Boinc doesn't continue crunching if you close Boinc manager software. So leave it on. You can follow your stats from projects your profile page and http://boincstats.com/ with user search to see all stats from all of your projects.
    You can run BOINC while you are chatting, watching movies or web surfing.

    Saturday, November 5, 2011

    Docking@Home


    Docking@Home is a project which uses Internet-connected computers to perform scientific calculations that aid in the creation of new and improved medicines. The project aims to help cure diseases such as Human Immunodeficiency Virus (HIV). Docking@Home is a collaboration between the University of Delaware, The Scripps Research Institute, and the University of California - Berkeley. It is part of the Dynamically Adaptive Protein-Ligand Docking System project and is supported by the National Science Foundation.

    How Does It Work?

    Before new drugs can be produced for laboratory testing, researchers must create molecular models and simulate their interactions to reveal possible candidates for effective drugs. This simulation is called docking. The combinations of molecules and their binding orientations are infinite in number. Simulating as many combinations as possible requires a tremendous amount of computing power. In order to reduce costs, researchers have decided that an effective means of generating this computing power is to distribute the tasks across a large number of computers.

    How Can I Help?

    By downloading a free program developed at University of California - Berkeley called BOINC, you can contribute your computer's idle processing cycles to the Docking@Home project. It's safe, easy to setup, and runs only when you want it to so it won't affect your ability to use your computer. If you are interested in finding out more information, you can read more about the project and the science behind it, or if you are ready to help, you can GET STARTED .

    Papers

    Wednesday, November 2, 2011

    First 24 hours with AMD "Bulldozer" FX-8120

       Monday afternoon i got AMD "Bulldozer" FX-8120, finally. Almost 3 weeks waiting cpus arrive to importers and it's finally up and crunching.  Corsair H100 (CDON.FI sells it for 87€) takes care of cooling the beast. Corsair H100 is one of the best cooling units in the market and i have tested it with 24/7 Boinc crunching with cpu(AMD Phenom II 1055T and from Monday FX-8120) and two gpus(Powercolor 6870 and Palit GTX460 1gb) 100% usage around the clock. There is alot of heat generated in the Xigmatek Midgard case. Corsair H100 and  six Scythe Gentle Typhoons 1850 rpm fans are doing excellent job with cooling.

       Overclocking is fun with "Bulldozer". So much tweaking and testing. I love this cpu. With stock voltages 4.0ghz. Only issue i am having is with APM dropping multiple to 14 with benchmarks like Cinebench , Prime95, OCCT, GeekBench and Linx. Issue only happens when stressing all 8 cores to 100% usage with single multihreaded software. If i run 8 times memtest with 100% core usage to all cores or running 8 boinc cpu tasks multiplier doesn't drop and i am getting 100% performance out from Bulldozer. Gigabyte GA-970A-UD3 bios doesn't have any options in it to disable APM function. I have to wait for new Bios and hope Gigabyte adds APM option to it.

       I will continue with my Overclocking experiments once i have my time.